Con la colaboración de

Scientific Program

12:00 - 15:00

Registration and posters set-up

12:30 - 12:50

Welcome Ceremony

Excmo. Sr. D. Guillermo Quindós, Vice-Chancellor of Social and Scientific Development and Transfer, University of the Basque Country

Excma. Sra. Dra. Marina Pollán, Director of Carlos III Institute of Health

Excmo. Sr. Juan María Aburto, Major of Bilbao

12:50 - 13:50

InterCIBER collaborations

CHAIRPERSON: Adolfo López de Munain


Eduardo Gallardo, Sant Pau Hospital, Barcelona

CIBER of Rare Diseases


Javier Meana, University of the Basque Country, Leioa

CIBER of Mental Health,


Leocadio Rodríguez Mañas, Getafe University Hospital

CIBER of Frailty and Aging


María Puy Portillo, University of the Basque Country

CIBER of Obesity and Nutrition

13:50 - 16:30 - Welcome cocktail & posters

15:00 - 16:30

Alzheimer’s disease and other related disorders I



A Noah’s ark approach to understand the molecular basis of prion diseases

Joaquín Castilla, CIBERINFEC, CIC-bioGUNE, Derio


Connecting microglial metabolic dysfunction with tau pathology: Clinical relevance for Alzheimer’s disease

Javier Vitorica, CIBERNED, Institute of Biomedicine of Seville


“Neurological aspects of post-COVID syndrome” (Online)

Tomás Segura, Albacete University

16:35 - 17:00 - Coffee break & posters

17:00 - 19:30

Alzheimer’s disease and other related disorders II



New era and new challenges in the treatment of Alzheimer's disease

Teresa Gómez-Isla, Massachusetts General Hospital


The role of TDP-43 in dementias: new target for therapeutic intervention

Ana Martínez Gil, CIBERNED, CIB-CSIC

18:15 - 19:30

Round table: Controversies around new therapies in Alzheimer’s disease. Pros and Cons

CHAIRPERSON: Teodoro del Ser

Pablo Martínez Lage, CIBERNED, CITA-Alzheimer, Donostia


Mircea Balasa, Hospital Clinic, IDIBAPS, Barcelona

“Población diana. Seguridad y factores de riesgo”

David Pérez, 12 de Octubre Hospital, Madrid

“Logística y aspectos económicos relacionados con la implementación de los nuevos tratamientos”

Joaquín Escudero, University Hospital of Valencia

“Impacto global en el SNS”

9:00 - 10:35

Parkinson’s disease and other motor neurodegenerative disorders I

Chairperson: Isabel Fariñas


Abnormal brain development sets the stage in Huntington disease

Sandrine Humbert, Paris Brain Institute, ICM


Analysis of thiamine deficiency in Huntington's disease as a biomarker of progression and for evaluation of therapeutic response

José J. Lucas, CIBERNED, CBMSO, CSIC-UAM, Madrid


Is missing heritability in late-onset ataxia revealed? Our single-center experience

Pablo Iruzubieta, CIBERNED, Biodonostia Institute, San Sebastián

10:35 - 11:00 - Coffee break & posters

11:00 - 13:05

Parkinson’s disease and other motor neurodegenerative disorders II



Striatal synaptic transmission and alpha-synuclein in Parkinson’s disease

Paolo Calabresi, Fondazione Policlinico Universitario Agostino Gemelli, Rome


Mapping intranasal nanoconjugates for Parkinson: MRI analysis of CNS targeting and biodistribution

Marta Martínez-Vicente, CIBERNED, Vall d’Hebron Research Institute, Barcelona


From neuronal vulnerability to gene therapy in Parkinson's disease - The role of focused ultrasound

Javier Blesa, CIBERNED, HM-CINAC, Móstoles (Madrid)


Autoimmunity against Renin-Angiotensin system in Parkinson’s Disease

Ana I. Rodríguez-Pérez, CIBERNED, University of Santiago

13:00 - 14:30 - Lunch & posters

14:30 - 16:30

Scientific Session III: Late-breaking news/poster highlights

CHAIRPERSON: Rosario Moratalla


Young Investigator Award

Ana Domingo Muelas, University of Pennsilvania, Philadelphia

“Post-transcriptional control of a stemness signature by RNA-binding protein MEX3A regulates murine adult neurogénesis”


Oral presentations of selected poster
Human biomodels to study glial bioenergetic in Parkinson’s disease

Paula Ramos-González CIBERNED, Achucarro Basque center for Neuroscience, Leioa

GIGYF2 rare variants as a genetic marker for Parkinson’s disease. Screening in a Basque population and systematic review.

Fernando Cardona CIBERNED, Instituto de Biomedidina de vallencia-CSIC

Light-dependent cAMP modulation in astrocytes trigger synaptic potentiation and behavioural changes in mice: role in Huntington’s Disease

Mercè Masana CIBERNED, INIDBAPS, University of Barcelona

Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality

Nicolás Capelo CIBERNED, University of Seville

A mammalian-specific Alex3/Gαq protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival

Yasmina Manso, CIBERNED, University of Barcelona

LncRNAs in the CNS of SOD1G93A mice: new potential biomarkers and intervention targets for ALS.

Tresa López-Royo, CIBERNED, University of Zaragoza

Fighting frontotemporal dementia: uncovering the potential of CB2 receptor antagonists

Isabel Lastres-Becker, CIBERNED, IRYCIS, Complutense University of Madrid

Multiomic analysis upon genetic removal of CSPα/DNAJC5 in adulthood links altered lipid homeostasis to neurodegeneration

Fátima Rubio, CIBERNED, Institute of Biomedicine of Seville

Distribution of NMDA receptors in cortex of Alzheimer´s disease patients: synaptic versus extrasynaptic membranes

Inmaculada Cuchillo-Ibáñez, CIBERNED, Miguel Hernandez University, Elche

16:30 - 17:00 - Coffee break & posters

17:00 - 18:05

Parkinson’s disease and other motor neurodegenerative disorders III

CHAIRPERSON: Jordi Pérez-Tur


Modifiers of penetrance in hereditary neurodegenerative diseases: Mechanisms of disease protection

Christine Klein, University Hispital Schleswig-Holstein, Lübeck


ER-mitochondria contact sites in neurodegeneration

Patricia Gómez-Suaga, CIBERNED, University of Extremadura, Cáceres

18:10 - 19:00

Colloquium with representatives of advocacy organizations

CHAIRPERSON: Adolfo López de Munain

Pedro Carrascal, Plataforma de Asociaciones

Karmele Zubizarreta, Asociación de Esclerosis Múltiple de Vizcaya, ADEMBI

María del Carmen Torregosa, Federación Española de Parkinson

Laura Román, Con P de Parkinson

Ruth Blanco y Miren Jaione Basarrate, Federacion Española de Personas afectadas por la Enfermedad de Huntington (FEPAEH-ACHE)

19:00 - 20:15

CIBERNED BOARD OF PIs (parallel session)

9:00 - 11:00

ALS and other neuromuscular disorders

Chairperson: Sonia Alonso-Martín


What do we know about ALS genetics?

Ammar Al-Chalabi, King’s College London


New insights in myasthenia gravis

Elena Cortés, CIBERER, Sant Pau Hospital, Barcelona


Behavioral aspects of IGF-I neurobiology

Jonathan Zagarra, CIBERNED, Achucarro Basque Center for Neuroscience, Leioa


The contribution of lipid dysfunction to AD and its relevance to diagnosis

Estela-Area-Gómez, CIB-CSIC, Madrid


ALS and energy metabolism

Ian Holt, CIBERNED, Biodonostia Institute, Donostia

11:25 - 12:00 - Coffee break & posters

12:00 - 14:00

Multiple Esclerosis, Neuroinflammation and neurodegeneration

CHAIRPERSON: Diego Clemente


New biomarkers in multiple sclerosis

Luisa María Villar, Ramón y Cajal University Hospital, Madrid


Microbiota and multiple esclerosis

Laura Moles, Biodonostia Institute, Donostia


Myelin as a brain energy source in health and disease

Carlos Matute, CIBERNED, Achucarro Basque Center for Neuroscience, University of the Basque Country, Leioa


Reactivating the GSK3b/Nrf2 axis in adrenoleukodystrophy prevents axonal degeneration: moving to the clinic” (Online)

Aurora Pujol, CIBERER, Bellvitge Hospital-IDIBELL, L'Hospitalet de Llobregat


Summary and concluding remarks. Farewell